GLP-1 True Out-of-Pocket Cost Calculator
Forecast realistic multi-month budgets based on your target medication, dosage escalation schedule, and required telehealth subscription fees.
True Out-of-Pocket Cost Calculator
Estimate realistic treatment costs accounting for dose titration and monthly membership fees over time.
Why Does GLP-1 Pricing Increase Over Time?
GLP-1 receptor agonists require a systematic dosage ramp (titration) to minimize gastrointestinal side effects like nausea and vomiting while allowing your body's metabolic receptors to adapt.
Standard Semaglutide Schedule
- Month 1: 0.25 mg weekly (Starter)
- Month 2: 0.50 mg weekly (Escalation)
- Month 3: 1.00 mg weekly (Intermediate)
- Month 4: 1.70 mg weekly (Therapeutic)
- Month 5+: 2.40 mg weekly (Max Maintenance)
Standard Tirzepatide Schedule
- Month 1: 2.5 mg weekly (Starter)
- Month 2: 5.0 mg weekly (Escalation)
- Month 3: 7.5 mg weekly (Intermediate)
- Month 4: 10.0 mg weekly (Therapeutic)
- Month 5+: 12.5 mg – 15.0 mg weekly (Max)
Because month 4+ requires significantly more milligrams of active pharmaceutical ingredient than month 1, providers on tiered pricing models will raise prices accordingly. Flat-rate clinics (such as Mochi Health or OrderlyMeds) absorb this cost variance, making them substantially more cost-effective for long-term patients.